Ossifying fibromyxoid tumour

Last revised by Henry Knipe on 3 Nov 2021

Ossifying fibromyxoid tumours are soft tissue tumours of uncertain lineage.

It typically manifests in adults. There may be a slight increased male predilection.

The clinical presentation can vary depending on location but usually tends to manifest as a slowly growing painless mass.

Its exact aetiology is not clear but a schwannian or chondroid origin has sometimes been favoured. It comprises of small round cells dispersed in a myxoid matrix and can contain bone, osteoid, and collagen elements.

It is reported to most often arise in the subcutaneous extremities. Other reported locations include

It is generally considered benign although recurrence following the resection can be common. Complete local resection is considered the best treatment in many cases.

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