Ovarian cystadenofibroma

Last revised by Ammar Ashraf on 4 Dec 2022

Citation, DOI, disclosures and article data

Citation:

Weerakkody Y, Ashraf A, Botz B, et al. Ovarian cystadenofibroma. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-13423

DOI:

https://doi.org/10.53347/rID-13423

Permalink:

https://radiopaedia.org/articles/13423

rID:

13423

Article created:

9 Apr 2011, Yuranga Weerakkody ◉

Disclosures:

At the time the article was created Yuranga Weerakkody had no recorded disclosures.

View Yuranga Weerakkody's current disclosures

Last revised:

4 Dec 2022, Ammar Ashraf ◉

Disclosures:

At the time the article was last revised Ammar Ashraf had no financial relationships to ineligible companies to disclose.

View Ammar Ashraf's current disclosures

Revisions:

9 times, by 7 contributors - see full revision history and disclosures

Systems:

Gynaecology

Tags:

cases

Synonyms:

Cystadenofibroma of the ovary (CAF)

Ovarian cystadenofibromas are a relatively uncommon benign epithelial ovarian tumour where the fibrous stroma remains a dominant component of the neoplasm. As a group, they are thought to represent ~1.7 % of all benign ovarian tumours ³.

Almost all cystadenofibromas are predominantly cystic on ultrasound with septations seen in ~30% of cases. Papillary projections or solid nodules have been sonographically seen in just over 50% of cases. Vascularisation can be present in just under 50% of cases with a typical pattern of peripheral vascularisation with scattered vessels of high blood flow impedance ⁹.

MRI

They can have either a pure cystic or complex cystic pattern with the solid components having a nodular or trabecular pattern ³.

Signal characteristics

T2: due to the stromal components the fibrous septa often have low signal while the cystic components can have high signal; this may give a "black sponge" like appearance ⁷
T1 C+ (Gd): septated component may show moderate enhancement ⁸

Treatment and prognosis

They generally tend to be benign tumours although the degree of epithelial proliferation and its relation to the stromal component of the tumour can be used for their classification as benign, borderline or malignant ⁵.

References

1. Jung SE, Lee JM, Rha SE et-al. CT and MR imaging of ovarian tumors with emphasis on differential diagnosis. Radiographics. 22 (6): 1305-25. doi:10.1148/rg.226025033 - Pubmed citation
2. Wasnik A, Elsayes K. Ovarian cystadenofibroma: A masquerader of malignancy. Indian J Radiol Imaging. 2010;20 (4): 297-9. doi:10.4103/0971-3026.73538 - Free text at pubmed - Pubmed citation
3. Cho SM, Byun JY, Rha SE et-al. CT and MRI findings of cystadenofibromas of the ovary. Eur Radiol. 2004;14 (5): 798-804. doi:10.1007/s00330-003-2060-z - Pubmed citation
4. Jung DC, Kim SH, Kim SH. MR imaging findings of ovarian cystadenofibroma and cystadenocarcinofibroma: clues for the differential diagnosis. Korean J Radiol. 7 (3): 199-204. Korean J Radiol (link) - Free text at pubmed - Pubmed citation
5. Byun JY. MR imaging findings of ovarian cystadenofibroma: clues for making the differential diagnosis from ovarian malignancy. Korean J Radiol. 7 (3): 153-5. Korean J Radiol (link) - Free text at pubmed - Pubmed citation
6. Outwater EK, Siegelman ES, Talerman A et-al. Ovarian fibromas and cystadenofibromas: MRI features of the fibrous component. J Magn Reson Imaging. 7 (3): 465-71. - Pubmed citation
7. Korbin CD, Brown DL, Welch WR. Paraovarian cystadenomas and cystadenofibromas: sonographic characteristics in 14 cases. Radiology. 1998;208 (2): 459-62. Radiology (abstract) - Pubmed citation
7. Takeuchi M, Matsuzaki K, Kusaka M et-al. Ovarian cystadenofibromas: characteristic magnetic resonance findings with pathologic correlation. J Comput Assist Tomogr. 27 (6): 871-3. J Comput Assist Tomogr (link) - Pubmed citation
8. Kim KA, Park CM, Lee JH et-al. Benign ovarian tumors with solid and cystic components that mimic malignancy. AJR Am J Roentgenol. 2004;182 (5): 1259-65. AJR Am J Roentgenol (full text) - Pubmed citation
9. Alcázar JL, Errasti T, Mínguez JA et-al. Sonographic features of ovarian cystadenofibromas: spectrum of findings. J Ultrasound Med. 2001;20 (8): 915-9. J Ultrasound Med (abstract) - Pubmed citation
10. Eurorad teaching files : Case 9059

Incoming Links

Promoted articles (advertising)

ADVERTISEMENT: Supporters see fewer/no ads

{"current_user":null,"inclusions":[{"imageId":594216,"studyId":12555,"caseSlug":"ovarian-serous-cystadenofibroma","caption":"Case 1: on ultrasound","thumbnail":"https://prod-images-static.radiopaedia.org/images/594216/d4897078708c14feea60bb750f2db1_big_gallery.jpg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":594238,"studyId":12556,"caseSlug":"ovarian-serous-cystadenofibroma","caption":"Case 1: on MRI","thumbnail":"https://prod-images-static.radiopaedia.org/images/594238/deb4f2943667ec4b3fcc52fef6fc97_big_gallery.jpg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":50773489,"studyId":79908,"caseSlug":"ovarian-cystadenofibroma","caption":"Case 2","thumbnail":"https://prod-images-static.radiopaedia.org/images/50773489/742bfa88b273fb0a1201cf03d50e17_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":55052251,"studyId":106725,"caseSlug":"left-ovarian-serous-cystadenocarcinoma-and-right-ovarian-cystadenofibroma","caption":"Case 3: right ovarian cystadenofibroma","thumbnail":"https://prod-images-static.radiopaedia.org/images/55052251/5_big_gallery.jpeg","isStack":false,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":55057251,"studyId":106746,"caseSlug":"ovarian-serous-cystadenofibroma-2","caption":"Case 4: serous cystadenofibroma","thumbnail":"https://prod-images-static.radiopaedia.org/images/55057251/Anonymize.Seq2.Ser3.Img20_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_unsubstantiated"},{"imageId":56401559,"studyId":114049,"caseSlug":"mucinous-ovarian-cystadenofibroma","caption":"Case 5: mucinous subtype","thumbnail":"https://prod-images-static.radiopaedia.org/images/56401559/AbdP_C__V__3.0__SPO__cor__cor_24_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"},{"imageId":60243784,"studyId":129059,"caseSlug":"ovarian-mucinous-cystadenofibroma","caption":"Case 6: ovarian mucinous cystadenofibroma","thumbnail":"https://prod-images-static.radiopaedia.org/images/60243784/a192c5c4815530a5bfcdf2261d403ab60fd1b021624fc19f6958bab945ad2497_big_gallery.jpeg","isStack":true,"diagnosticCertainty":"confirmed_substantiated"}],"ddx_inclusions":[],"lang":"gb"}