Ovarian cystadenofibroma

An ovarian cystadenofibroma (CAF) is a relatively uncommon benign epithelial ovarian tumor where the fibrous stroma remains a dominant component of the neoplasm. As a group they are thought to represent ~1.7 % of all benign ovarian tumors 3.

Although generally classified as an epithelial tumor, a cystadenofibroma contains both epithelial and stromal components.

Recognized histological sub types include 3,5

Lesions can be bilateral in ~15% of cases.

Almost all cystadenofibromas are predominantly cystic on ultrasound with septations seen in ~30% of cases. Papillary projections or solid nodules have be sonographically seen in just over 1/2 of cases. Vascularization can be present in just under 1/2 of cases with typical pattern of peripheral vascularization with scattered vessels of high blood flow impedance 9.

They can have a either a pure cystic or complex cystic pattern with the solid components having a nodular or trabecular pattern 3.

Reported signal characteristics in general include

  • T2: due to the stromal components the fibrous septa often have low signal while the cystic components can have high signal; this may give a "black sponge" like appearance 7
  • T1 C+ (Gd): septated component may show moderate enhancement 8

They generally tend to be benign tumors although the degree of epithelial proliferation and its relation to the stromal component of the tumor can used for their classification as benign, borderline or malignant 5.

Share article

Article information

rID: 13423
System: Gynaecology
Tag: cases
Synonyms or Alternate Spellings:
  • Cystadenofibroma of the ovary

Support Radiopaedia and see fewer ads

Cases and figures

  • There is a multil...
    Case 1 : serous cystadenofibroma : US
    Drag here to reorder.
  • Case 1 : serous cystadofibroma : MRI T2
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.