Pancreatic mesenchymal neoplasms

Changed by Matt A. Morgan, 10 Feb 2016

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Pancreatic ~~nonepithelial~~mesenchymal neoplasms

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Pancreatic ~~nonepithelial~~mesenchymal neoplasms ~~(which include~~(or pancreatic ~~mesenchymal~~nonepithelial neoplasms) are a group of rare pancreatic neoplasms that arise from the structural elements of the pancreas (nerves, fat, lymph), rather than from the exocrine or endocrine cells of the pancreas. Neoplasms from exocrine and endocrine cells ~~(derived from endoderm)~~ result in more familiar pancreatic neoplasms such as pancreatic ductal adenocarcinoma, IPMN, and pancreatic endocrine tumors (formerly termed "islet cell tumors").

Epidemiology

Pancreatic ~~non epithelial~~mesenchymal neoplasms are rare and represent at most 1-2% of pancreatic neoplasms².

Pathology

Pancreatic nonepithelial tumors include

Benign

pancreatic neurofibroma
pancreatic schwannoma
pancreatic ganglioneuroma
pancreatic desmoid tumor
pancreatic lipoma
pancreatic perivascular epithelioid cell tumor (PEComa)
pancreatic mature cystic teratoma (dermoid)
pancreatic lymphangioma

Malignant

Radiographic features

A disparate group of tumors, they have different imaging appearances, based on their underlying histology. As a group, these neoplasms tend to better-marginated than the more infiltrative pancreatic ductal adenocarcinoma ¹.

-<p><strong>Pancreatic nonepithelial neoplasms</strong> (which include <strong>pancreatic mesenchymal neoplasms</strong>) are a group of rare <a title="Pancreatic neoplasms" href="/articles/pancreatic-neoplasms">pancreatic neoplasms</a> that arise from the structural elements of the pancreas (nerves, fat, lymph), rather than from the exocrine or endocrine cells of the pancreas. Neoplasms from exocrine and endocrine cells (derived from endoderm) result in more familiar pancreatic neoplasms such as <a title="Pancreatic ductal adenocarcinoma" href="/articles/pancreatic-ductal-carcinoma">pancreatic ductal adenocarcinoma</a>, <a title="IPMN" href="/articles/intraductal-papillary-mucinous-neoplasm">IPMN</a>, and <a title="Pancreatic endocrine tumors" href="/articles/endocrine-tumours-of-the-pancreas">pancreatic endocrine tumors</a> (formerly termed "islet cell tumors").</p><h4>Epidemiology</h4><p>Pancreatic non epithelial neoplasms are rare and represent at most 1-2% of pancreatic neoplasms.</p><h4>Pathology</h4><p>Pancreatic nonepithelial tumors include</p><h5>Benign</h5><ul>
+<p><strong>Pancreatic mesenchymal neoplasms</strong> (or <strong>pancreatic nonepithelial neoplasms</strong>) are a group of rare <a href="/articles/pancreatic-neoplasms">pancreatic neoplasms</a> that arise from the structural elements of the pancreas (nerves, fat, lymph), rather than from the exocrine or endocrine cells of the pancreas. Neoplasms from exocrine and endocrine cells result in more familiar pancreatic neoplasms such as <a href="/articles/pancreatic-ductal-carcinoma">pancreatic ductal adenocarcinoma</a>, <a href="/articles/intraductal-papillary-mucinous-neoplasm">IPMN</a>, and <a href="/articles/endocrine-tumours-of-the-pancreas">pancreatic endocrine tumors</a> (formerly termed "islet cell tumors").</p><h4>Epidemiology</h4><p>Pancreatic mesenchymal neoplasms are rare and represent at most 1-2% of pancreatic neoplasms <sup>2</sup>.</p><h4>Pathology</h4><p>Pancreatic nonepithelial tumors include</p><h5>Benign</h5><ul>
~~-<li><a title="Pancreatoblastoma" href="/articles/pancreatoblastoma">pancreatoblastoma</a></li>~~
~~-<li><a title="Pancreatic lymphoma" href="/articles/pancreatic-lymphoma">pancreatic lymphoma</a></li>~~
+<li><a href="/articles/pancreatoblastoma">pancreatoblastoma</a></li>
+<li><a href="/articles/pancreatic-lymphoma">pancreatic lymphoma</a></li>

References changed:

2. Ferrozzi F, Zuccoli G, Bova D, Calculli L. Mesenchymal Tumors of the Pancreas: CT Findings. J Comput Assist Tomogr. 2000;24(4):622-7. <a href="https://doi.org/10.1097/00004728-200007000-00021">doi:10.1097/00004728-200007000-00021</a>
1. Manning M, Srivastava A, Paal E, Gould C, Mortele K. Nonepithelial Neoplasms of the Pancreas: Radiologic-Pathologic Correlation, Part 1—Benign Tumors:From the Radiologic Pathology Archives. Radiographics. 2016;36(1):123-41. <a href="https://doi.org/10.1148/rg.2016150212">doi:10.1148/rg.2016150212</a>

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