Papillary cystadenomas of the epididymis are the second most common benign tumors of the epididymis after adenomatoid tumors and are common in patients with von Hippel-Lindau disease (vHL).
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Clinical presentation
Papillary cystadenomas are usually asymptomatic.
Epidemiology
They are more common in young men (20-40 years) 2. Approximately 30% of patients have vHL and ~35% (range 10-60%) of patients with vHL have papillary cystadenoma(s) 1,2.
Radiographic features
Lesions are usually arising from the head of the epididymis and can present as a cystic lesion with a thick wall and several peripheral solid nodules with increased vascularity, partially or completely cystic or solid lesion and measuring up to 3 cm in diameter 1.
Differential diagnosis
Considerations include:
Practical points
Patients with bilateral papillary cystadenomas of the epididymis should be considered for vHL screening 2.