Parkinson-plus syndrome

Last revised by Daniel J Bell on 16 Nov 2020

Parkinson-plus syndromes are a loose group of neurodegenerative disorders that are characterized by features of Parkinson disease but with other neurological symptoms/signs. They have a poor response to levodopa, and mostly have fairly characteristic neuroimaging features. 

Conditions included in Parkinson-plus syndrome include 2,4:

The importance of recognizing Parkinson-plus syndromes is that ~25% of patients diagnosed with Parkinson disease end up being diagnosed with a Parkinson-plus syndrome instead 3. Early recognition of features of Parkinson-plus on imaging may help determine an earlier diagnosis and more appropriate treatment. 

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.