Revision 2 for 'Pathological fracture risk (Harrington criteria)'

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Pathological fracture risk: Harrington criteria

Harrington criteria can be used to predict which skeletal metastases are at high risk of pathological fracture and should undergo prophylactic internal fixation. It preceded Mirel classification for impending pathological fracture but has not been validated and its use is debated. 


  • >50% cortical bone destruction
  • lesion >2.5 in size
  • pathological avulsion fracture of the lesser trochanter
  • function pain after radiation therapy

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