Persistent right umbilical vein

A persistent right umbilical vein (PRUV) is an uncommon vascular anomaly which is often detected in utero.

The estimated prevalence is ~2 per 1000 births 1,2.

In the normal situation, the right umbilical vein begins to obliterate in the ~4th week of gestation and disappears by the 7th week. With a PRUV, the right umbilical vein remains open and the left umbilical vein usually obliterates. A PRUV may also be supernumerary 6.

A PRUV can be intra- or extrahepatic. The former is much commoner.

Numerous associations have been described (albeit at relatively low rates 3,9). They are commoner with the extrahepatic type and include:

It is usually detected in the 2nd to 3rd trimester. Assessment is usually made in the axial plane and color Doppler is often required. An intrahepatic persistent right umbilical vein may be seen as an umbilical vein abnormally connected to the right portal vein and the fetal gallbladder is positioned medial to the PRUV. 

When additional anomalies are ruled out, a PRUV in isolation carries a generally favourable outcome 1,9.

If a persistent right umbilical vein is detected, a careful sonographic anatomical survey is generally recommended to rule out more serious congenital malformations 10.

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Article information

rID: 13564
Section: Anatomy
Synonyms or Alternate Spellings:
  • Persistent right umbilical vein (PRUV)
  • PRUV
  • Persistence of the right umbilical vein
  • Right umbilical vein persistence

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