Revision 11 for 'Pineal parenchymal tumor with intermediate differentiation'

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Pineal parenchymal tumor with intermediate differentiation

Pineal parenchymal tumor with intermediate differentiation are, as the name suggests tumors which fall between pineocytoma (well differentiated, WHO grade I) and pineoblastomas (poorly differentiated, WHO grade IV) and are considered WHO grade II / III tumors 2. This is tumor of middle age adults with male and females are affected equally. 

Their pathology, radiographic appearance and biological behavior are also intermediate. They may invade adjacent structures and also spread along CSF.

Pathologically they do not demonstrate the highly differentiated appearance of pineocytomas, but also lack the malignant small blue cell appearance of a pineoblastoma. 

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