Revision 13 for 'Pineal parenchymal tumor with intermediate differentiation'All Revisions - View changeset
Pineal parenchymal tumor with intermediate differentiation
Pineal parenchymal tumors with intermediate differentiation (PPTID) are, as the name suggests, tumors which fall between pineocytoma (well differentiated, WHO grade I) and pineoblastomas (poorly differentiated, WHO grade IV) and are considered WHO grade II / III tumors 2. This is a tumor of middle age adults with male and females affected equally.
Their pathology, radiographic appearance and biological behavior are also intermediate. They may invade adjacent structures and also spread along CSF (imaging of the intire craniospinal axis is required 3).
Pathologically they do not demonstrate the highly differentiated appearance of pineocytomas, but also lack the malignant small blue cell appearance of a pineoblastoma.