Poliodystrophies are neurological disease dominated by grey-matter involvement as opposed to leukodystrophies (dominated by white matter involvement) or pandystrophies (both white and grey matter involved).
The poliodystrophy group are defined by predominant grey matter involvement, but some degree of white matter involvement is often present.
The typical poliodystrophy group diseases are:
- respiratory chain disorders
- organic acidopathies
- storage diseases (some)