Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Campos A, Knipe H, et al. Premature thelarche. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-72288
Premature thelarche is the onset of female breast development before age 7–8 years.
Pathology
As with age-appropriate thelarche, premature thelarche may be asymmetric or unilateral.
Premature thelarche may occur as an isolated event or as part of precocious puberty. Isolated premature thelarche generally occurs in girls aged 1-3 years and is non-progressive.
Radiographic features
Radiological evaluation for suspected precocious puberty should include a bone age assessment and abdominal and pelvic sonography to look for evidence of maturation of the uterus and ovaries. In addition, the ovaries and adrenal glands should be evaluated for estrogen-producing lesions, including:
Ultrasound
At sonography, premature thelarche appears as normal developing breast tissue without a discrete lesion.
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1. Ellen M. Chung, Regino Cube, Gregory J. Hall, Candela González, J. Thomas Stocker, Leonard M. Glassman. Breast Masses in Children and Adolescents: Radiologic-Pathologic Correlation1. (2009) RadioGraphics. 29 (3): 907-31. doi:10.1148/rg.293095010 - Pubmed
-
2. Cristián J. García, Aníbal Espinoza, Víctor Dinamarca, Oscar Navarro, Alan Daneman, Hernán García, Andreina Cattani. Breast US in Children and Adolescents1. (2000) RadioGraphics. 20 (6): 1605-12. doi:10.1148/radiographics.20.6.g00nv171605 - Pubmed
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3. Weinstein SP, Conant EF, Orel SG, Zuckerman JA, Bellah R. Spectrum of US findings in pediatric and adolescent patients with palpable breast masses. (2000) Radiographics : a review publication of the Radiological Society of North America, Inc. 20 (6): 1613-21. doi:10.1148/radiographics.20.6.g00nv091613 - Pubmed
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4. Youn I, Park SH, Lim IS, Kim SJ. Ultrasound assessment of breast development: distinction between premature thelarche and precocious puberty. (2015) AJR. American journal of roentgenology. 204 (3): 620-4. doi:10.2214/AJR.14.12565 - Pubmed
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