Renal leiomyoma
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Article Attributes
Renal leiomyomas are benign tumours of the kidney originating from smooth muscle cells of the renal capsule, pelvis, calices ,calyces or blood vessels.
There is a 4% to 5-5.5% prevalence based on autopsy findings1.
Clinical presentation
Renal leiomyomas are usually incidental findings.
In In symptomatic cases, these lesions can cause abdominal/flank pain and/or palpable mass1.
Pathology
At macroscopic examination, leiomyomas are typically well-demarcated, solid , firm nodules with rare calcifications and cystic changes, without necrosis.
Microscopically, spindle cells with few nuclear polymorphisms and no mitotic activity are arranged in intersecting fascicles2.
Diagnosis
Diagnosis in based on histologichistological analysis.
Radiographic features
Ultrasound
UltrasoundUltrasound may display a solid or cystic mass and allow for identification of a plane between the tumour and kidney, but has very poor specificity1.
DSA-angiography
Angiographic appearance can be either hypo- or hyper-vascular and features indicative of malignancy, such as vessel encasement, renal vein invasion or arteriovenous shunting, are absent1.
CT
Computed tomography scanning provides improved anatomic definition and reveals well-circumscribed margins, a capsular/subcapsular or peripelvic origin, minimal parenchymal distortion, and no evidence of extra-renal invasion1.
Some think density Some suggest attenuation value, location and margins of the lesion can help to adressaddress the diagnosis of renal leiomyoma2.
-<p><strong>Renal leiomyomas </strong>are benign tumours of the kidney originating from smooth muscle cells of the renal capsule , pelvis , calices , or blood vessels.</p><p>There is a 4% to 5.5% prevalence based on autopsy findings<sup>1</sup>.</p><h4>Clinical presentation</h4><p>Renal leiomyomas are usually incidental findings.</p><p>In symptomatic cases, these lesions can cause abdominal/flank pain and/or palpable mass<sup>1</sup>.</p><h4>Pathology</h4><p>At macroscopic examination, leiomyomas are typically well-demarcated, solid , firm nodules with rare calcifications and cystic changes, without necrosis.</p><p>Microscopically, spindle cells with few nuclear polymorphisms and no mitotic activity are arranged in intersecting fascicles<sup>2</sup>.</p><h4>Diagnosis</h4><p>Diagnosis in based on histologic analysis.</p><p> Ultrasound may display a solid or cystic mass and allow for identification of a plane between the tumour and kidney, but has very poor specificity<sup>1</sup>.</p><p>Angiographic appearance can be either hypo- or hyper-vascular and features indicative of malignancy, such as vessel encasement, renal vein invasion or arteriovenous shunting, are absent<sup>1</sup>.</p><p>Computed tomography scanning provides improved anatomic definition and reveals well-circumscribed margins, a capsular/subcapsular or peripelvic origin, minimal parenchymal distortion, and no evidence of extra-renal invasion<sup>1</sup>.</p><p>Some think density , location and margins of the lesion can help to adress the diagnosis of renal leiomyoma<sup>2</sup>.</p>- +<p><strong>Renal leiomyomas </strong>are benign tumours of the kidney originating from smooth muscle cells of the renal capsule, pelvis, calyces or blood vessels.</p><p>There is a 4-5.5% prevalence based on autopsy findings<sup>1</sup>.</p><h4>Clinical presentation</h4><p>Renal leiomyomas are usually incidental findings. In symptomatic cases, these lesions can cause abdominal/flank pain and/or palpable mass<sup>1</sup>.</p><h4>Pathology</h4><p>At macroscopic examination, <a title="leiomyoma" href="/articles/leiomyoma">leiomyomas</a> are typically well-demarcated, solid , firm nodules with rare calcifications and cystic changes, without necrosis.</p><p>Microscopically, spindle cells with few nuclear polymorphisms and no mitotic activity are arranged in intersecting fascicles<sup>2</sup>.</p><h4>Diagnosis</h4><p>Diagnosis in based on histological analysis.</p><h4>Radiographic features</h4><h5>Ultrasound</h5><p>Ultrasound may display a solid or cystic mass and allow for identification of a plane between the tumour and kidney, but has very poor specificity<sup>1</sup>.</p><h5>DSA-angiography</h5><p>Angiographic appearance can be either hypo- or hyper-vascular and features indicative of malignancy, such as vessel encasement, renal vein invasion or arteriovenous shunting, are absent<sup>1</sup>.</p><h5>CT</h5><p>Computed tomography scanning provides improved anatomic definition and reveals well-circumscribed margins, a capsular/subcapsular or peripelvic origin, minimal parenchymal distortion, and no evidence of extra-renal invasion<sup>1</sup>. Some suggest attenuation value, location and margins of the lesion can help to address the diagnosis of renal leiomyoma<sup>2</sup>.</p>
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