Retinopathy of prematurity (ROP) (formerly referred to as retrolental fibroplasia) is an ocular condition seen in the infant population. It often occurs bilaterally, although usually with significant asymmetry 1.
There is often a history of premature delivery, low birth weight, and/or prolonged ventilatory support.
It occurs due to traction retinal detachment as a result of regression of the neovascularization secondary to the prolonged oxygen therapy. It mostly involves the temporal side of the globe.
The globes are usually asymmetrically small or even normal. Calcification can occur but is rare.
- 1. Kadom N, Sze RW. Radiological reasoning: leukocoria in a child. AJR Am J Roentgenol. 2008;191 (3): S40-4. doi:10.2214/AJR.07.7022 - Pubmed citation
- 2. Hopper KD, Sherman JL, Boal DK. Abnormalities of the orbit and its contents in children: CT and MR imaging findings. AJR Am J Roentgenol. 1991;156 (6): 1219-24. AJR Am J Roentgenol (citation) - Pubmed citation