Sandwich sign (mesentery)

Last revised by Mohammadtaghi Niknejad on 6 Dec 2022

A sandwich sign, sometimes known as a hamburger sign, refers to a mesenteric nodal mass, either para-aortic or not, giving an appearance of a hamburger. Confluent lymphadenopathy on both sides of the mesenteric vessels gives rise to an appearance described as the sandwich sign 2.

The sign is specific for mesenteric lymphoma (typically non-Hodgkin), unless the patient has had a transplant. If so, post-transplant lymphoproliferative disorder should be considered 1.

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