Scirrhous carcinoma (breast)
Last revised by Paul A. Kohanteb on 4 Mar 2024
Citation, DOI, disclosures and article data
Citation:
Radswiki T, Kohanteb P, Luijkx T, et al. Scirrhous carcinoma (breast). Reference article, Radiopaedia.org (Accessed on 24 Apr 2024) https://doi.org/10.53347/rID-15448
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rID:
15448
Article created:
18 Oct 2011,
The Radswiki ◉
Disclosures:
At the time the article was created The Radswiki had no recorded disclosures.
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Last revised:
4 Mar 2024,
Paul A. Kohanteb
Disclosures:
At the time the article was last revised Paul A. Kohanteb had no financial relationships to ineligible companies to disclose.
View Paul A. Kohanteb's current disclosures
Revisions:
5 times, by
5 contributors -
see full revision history and disclosures
Systems:
Synonyms:
- Scirrhous breast carcinoma
- Scirrhous carcinoma of breast
Scirrhous carcinoma of the breast is a pathological subtype of breast cancer. It is a subtype of invasive ductal carcinoma not otherwise specified and presents as a hard lump. The proportion of pathologic lymph node metastasis among scirrhous carcinomas is significantly higher than that among carcinomas of other histological types 2.
Related Pathology:
Scirrhous carcinoma of the breast can metastasize to the orbit resulting in enophthalmos via a desmoplastic reaction 3 4.
References
- 1. Van bogaert LJ, Maldague P. Scirrhous carcinoma of the female breast. Invest Cell Pathol. 3 (4): 377-82. - Pubmed citation
- 2. Nozoe T, Oyama T, Mori E et-al. Clinicopathologic significance of an immunohistochemical expression of p27 in scirrhous carcinoma of the breast. Breast Cancer. 2007;14 (3): 277-80. Breast Cancer (link) - Pubmed citation
- 3. Novitskaya E & Rene C. Enophthalmos as a Sign of Metastatic Breast Carcinoma. CMAJ. 2013;185(13):1159. doi:10.1503/cmaj.120726 - Pubmed
- 4. Meltzer D, Chang A, Shatzkes D. Case 152: Orbital Metastatic Disease from Breast Carcinoma. Radiology. 2009;253(3):893-6. doi:10.1148/radiol.2533081926 - Pubmed
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