Scleritis refers to inflammation of the sclera. It has a wide range of causes.

It can affect age group but usually those between ages 30 and 50 years. There is a recognized increased female predilection (F:M of ~2:1).

Information on the pathogenesis of scleritis is limited due to a lack of published data. However a predominant role for T cells in the inflammatory process has been postulated 1.

Scleritis can be associated with several systemic infective as well as non-infective systemic conditions which include 1:

One classification system is the Watson and Hayreh system which divides scleritis into anterior and posterior forms based upon the anatomic distribution.

  • anterior scleritis
    • diffuse anterior scleritis
    • nodular anterior scleritis
    • necrotizing anterior scleritis with inflammation
    • scleromalacia perforans (necrotizing anterior scleritis without inflammation)
  • posterior scleritis

Ocular ultrasound may play a role in the diagnosis and management of posterior scleritis.

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Article information

rID: 37414
Synonyms or Alternate Spellings:
  • Inflammation of the sclera
  • Scleral inflammatory disease

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