Scleroedema of Buschke

Last revised by Daniel J Bell on 7 Jul 2021

Scleroedema of Buschke, also known as scleroedema diabeticorum, is a dermal complication of diabetes mellitus, streptococcus infections and monoclonal gammopathies 1-3.

Risk factors for scleroedema of Buschke are 3-6:

  • prolonged duration of diabetes mellitus
  • obesity
  • chronic insulin dependence

The cardinal soft tissue changes are hardening and thickening of the dermis in the region of the shoulder, back and region of the neck.

Breathing difficulties and shoulder movement impairment may occur due to limitations imposed by these soft tissue changes.

Scleroedema of Buschke is characterised by non-pitting swelling and thickening of skin secondary to the deposition of collagen and amino glycans in the dermis 2,3,5

Phototherapy, physiotherapy, corticosteroids, antibiotics, intravenous immunoglobulin and tight glycaemic control are the main treatment options. Partial remission of the disease is documented in most of the cases 6.

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