Single layer (or lamellar) periosteal reaction is a uniformly dense, single thin layer of new bone about 1-2 mm from the cortical surface. It usually denotes an acute or subacute pathological process. Passive hyperemia causes increased osteoblastic activity and production of new bone.
Pathology
Etiology
- premature infants for up to 6 months
- early fracture healing
- stress fracture
- osteosarcoma
- osteomyelitis
- Langerhans cell histiocytosis
- metastasis
- osteoid osteoma
- aneurysmal bone cyst (ABC)
- Ewing sarcoma
- giant cell tumor (GCT)
- leukemia
- chronic venous insufficiency