Sitz marker study

Andrew Murphy and Dr Matt A. Morgan et al.

The Sitz marker study is an older technique to estimate colonic transit time. 

In constipation, it can help distinguish between slow colonic transit and a defecation disorder.

The patient ingests a number of radiopaque markers (plastic rings containing radiopaque material) in a meal and abdominal radiographs are obtained to monitor the clearance of the rings from the colon.

Normal colonic transit time is 20-56 hours, and most adults will clear all the markers in 4-5 days.

Laxatives (and possibly GI-active medications) should be temporarily discontinued, otherwise, no special preparation is needed.

Three main techniques are used:

  • 20 or 24 markers are ingested in a single dose, and then serial daily abdominal radiographs are obtained (more common)

or

  • 20 or 24 markers are ingested and a single abdominal radiograph is obtained six days later

or

  • 10 markers are ingested every day for three days and an abdominal radiograph is obtained on days four, seven, and ten

Most define <20% of the original rings at five days as normal. For instance, if 24 rings are used, then <5 rings should be present in five days. 

If using 20 rings and daily radiographs, some use the schedule:

  • day 1: ≤16 rings
  • day 2: ≤8 rings
  • day 3: ≤4 rings
  • day 4: ≤2 rings
  • day 5: ≤1 ring
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Article information

rID: 37753
Section: Radiography
Tag: refs, colon
Synonyms or Alternate Spellings:
  • Sitzmark colon transit test
  • Sitz marker study
  • Colon motility Test
  • Sitzmark Study
  • Colon transit time study
  • Colon transit study
  • Sitz markers
  • Colonic transit study (Sitz markers)

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Cases and figures

  • In this patient, ...
    Case 1: first day
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  • A zoomed-in view ...
    Case 1: the Sitz markers (zoomed in)
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  • Case 2
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  • Case 3: normal transit study
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