Technetium 99m-methyl diphosphonate

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TcTechnetium 99m ~~MDP~~-methyl diphosphonate

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Technetium 99m-methyl diphosphonate (99mTc MDP) is a radioisotope used in nuclear medicine especially for bone scans. ~~MDP stands for methylene di-phosphonate. Any~~ Any disease process which results in extracellular fluid expansion will lead to accumulation of this isotope.

~~Uses~~

Radionuclide profile

~~subacute~~photon energy: 140 keV
physical half life: 6 hours
critical organ: bladder

Uses

osteomyelitis
fractures, including stress and ~~chronic bone infections~~insufficiency fractures
malignancy, e.g. osteoid osteoma, bone metastases, soft tissue sarcomas
painful scoliosis
post traumatic hematomas, myositis ossificans
, heterotopic ossification
~~post traumatic hematomas~~
~~musculoskeletal stress~~
~~bone metastases~~
tumoral calcinosis
metastatic pulmonary calcification
sickle cell disease

-<p><strong>Technetium 99m MDP</strong> is a radioisotope used in nuclear medicine especially for bone scans. MDP stands for methylene di-phosphonate. Any disease process which results in extracellular fluid expansion will lead to accumulation of this isotope.</p><h5>Uses</h5><ul>
~~-<li>subacute and chronic bone infections</li>~~
~~-<li><a href="/articles/osteoid-osteoma">osteoid osteoma</a></li>~~
+<p><strong>Technetium 99m-methyl diphosphonate </strong>(<strong>99mTc MDP</strong>) is a radioisotope used in nuclear medicine especially for <a href="/articles/bone-scan">bone scans</a>. Any disease process which results in extracellular fluid expansion will lead to accumulation of this isotope.</p><h4>Radionuclide profile</h4><ul>
+<li>photon energy: 140 keV</li>
+<li>physical half life: 6 hours</li>
+<li>critical organ: <a href="/articles/urinary-bladder">bladder</a>
+</li>
+</ul><h4>Uses</h4><ul>
+<li><a title="Osteomyelitis" href="/articles/osteomyelitis">osteomyelitis</a></li>
+<li>fractures, including <a title="Stress fracture" href="/articles/stress-fractures">stress</a> and <a title="Insufficiency fractures" href="/articles/insufficiency-fracture">insufficiency fractures</a>
+</li>
+<li>malignancy, e.g. <a href="/articles/osteoid-osteoma">osteoid osteoma</a>, <a href="/articles/skeletal-metastases">bone metastases</a>, <a href="/articles/soft-tissue-sarcoma-1">soft tissue sarcomas</a>
+</li>
~~-<li><a href="/articles/soft-tissue-sarcoma-1">soft tissue sarcomas</a></li>~~
~~-<li><a href="/articles/heterotopic-ossification">heterotopic ossification</a></li>~~
~~-<li>post traumatic hematomas</li>~~
~~-<li>musculoskeletal stress</li>~~
~~-<li><a href="/articles/skeletal-metastases">bone metastases</a></li>~~
~~-<li><a href="/articles/tumoral-calcinosis">tumoral calcinosis</a></li>~~
~~-<li><a href="/articles/myositis-ossificans-1">myositis ossificans</a></li>~~
~~-<li><a href="/articles/metastatic-calcification">metastatic calcification</a></li>~~
~~-<li><a href="/articles/sickle-cell-disease">sickle cell disease</a></li>~~
+<li>post traumatic hematomas, <a href="/articles/myositis-ossificans-1">myositis ossificans</a>, <a href="/articles/heterotopic-ossification">heterotopic ossification</a>
+</li>
+<li><a title="Tumoral calcinosis" href="/articles/tumoral-calcinosis">tumoral calcinosis</a></li>
+<li><a title="Metastatic pulmonary calcification" href="/articles/metastatic-pulmonary-calcification">metastatic pulmonary calcification</a></li>
+<li><a title="Sickle cell disease" href="/articles/sickle-cell-disease">sickle cell disease</a></li>

References changed:

4. Chopra A. 99mTc-Methyl diphosphonate. 2007 Mar 29 [Updated 2009 Aug 24]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013. Available from: http://www.ncbi.nlm.nih.gov/books/NBK24575/
5. Weissleder R, Wittenberg J, Harisinghani MMGH et-al. Primer of Diagnostic Imaging. Mosby. (2011) ISBN:0323065384. <a href="http://books.google.com/books?vid=ISBN0323065384">Read it at Google Books</a> - <a href="http://www.amazon.com/gp/product/0323065384">Find it at Amazon</a><span class="ref_v3"></span>

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