Testicular choriocarcinoma is a type of non-seminomatous germ cell tumor.
Incidence peaks at around 20-30 years of age.
Can be variable with some patients initially presenting with metastates.
It is most commonly detected as a component of a mixed malignant germ cell tumor and observed in about 7-8% of testicular tumors. It is extremely rare in pure form, choriocarcinoma comprising only 0.2-0.6% of all testis tumors.
b-HCG levels tend to be elevated
Treatment and prognosis
It is considered an aggressive malignancy. Choriocarcinoma can often spread haematogenously. Treatment options include orchiectomy +/- combination chemotherapy.
- 1. Reilley MJ, Pagliaro LC. Testicular choriocarcinoma: a rare variant that requires a unique treatment approach. (2015) Current oncology reports. 17 (2): 2. doi:10.1007/s11912-014-0430-0 - Pubmed
- 2. Kreydin EI, Barrisford GW, Feldman AS, Preston MA. Testicular cancer: what the radiologist needs to know. (2013) AJR. American journal of roentgenology. 200 (6): 1215-25. doi:10.2214/AJR.12.10319 - Pubmed
- 3. Matsumoto JS, Hoffman AD. Pediatric case of the day. Testicular choriocarcinoma. (1993) AJR. American journal of roentgenology. 160 (6): 1334-5. doi:10.2214/ajr.160.6.8498254 - Pubmed
- 4. Coursey Moreno C, Small WC, Camacho JC, Master V, Kokabi N, Lewis M, Hartman M, Mittal PK. Testicular tumors: what radiologists need to know--differential diagnosis, staging, and management. (2015) Radiographics : a review publication of the Radiological Society of North America, Inc. 35 (2): 400-15. doi:10.1148/rg.352140097 - Pubmed