Testicular choriocarcinoma

Last revised by Joshua Yap on 11 Feb 2023

Testicular choriocarcinoma is a type of non-seminomatous germ cell tumor

Incidence peaks at around 20-30 years of age.

Can be variable with some patients initially presenting with metastases.

It is most commonly detected as a component of a mixed malignant germ cell tumor and observed in about 7-8% of testicular tumors. It is extremely rare in pure form, choriocarcinoma comprising only 0.2-0.6% of all testis tumors.

b-HCG levels tend to be elevated.

It is considered an aggressive malignancy. Choriocarcinoma can often spread hematogenously. Treatment options include orchiectomy +/- combination chemotherapy.

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