Top of the basilar syndrome

Changed by Vincent Tatco, 30 Dec 2016

Updates to Article Attributes

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Top of the basilar syndrome, (alsoalso known as rostral brainstem infarction), occurs when there is thromboembolic occlusion of the top of the basilar artery. This results in bilateral thalamic ischaemia due to occlusion of perforator vessels.

Clinical presentation

Clinically, top of the basilar syndrome is characterised by:

  • visual and oculomotor deficits
  • behavioural abnormalities
  • somnolence, hallucinations and dreamlike behaviour
  • motor dysfunction is often absent

Radiographic features

On CT the finding that should not be missed is that of a hyperdense basilar artery and imaging features are discussed further in the more general article on acute basilar basilar artery occlusion

Angiography (CT, MR, catheter) can be used to confirm the finding, demonstrating a filling defect. 

Differential diagnosis

The pattern of established infarction can be mimicked by mimicked by:

  • -<p><strong>Top of the basilar syndrome</strong>, (also known as <strong>rostral brainstem infarction</strong>) occurs when there is thromboembolic occlusion of the top of the <a href="/articles/basilar-artery">basilar artery</a>. This results in bilateral thalamic ischaemia due to occlusion of perforator vessels.</p><h4>Clinical presentation</h4><p>Clinically, top of the basilar syndrome is characterised by :</p><ul>
  • +<p><strong>Top of the basilar syndrome</strong>, also known as <strong>rostral brainstem infarction</strong>, occurs when there is thromboembolic occlusion of the top of the <a href="/articles/basilar-artery">basilar artery</a>. This results in bilateral thalamic ischaemia due to occlusion of perforator vessels.</p><h4>Clinical presentation</h4><p>Clinically, top of the basilar syndrome is characterised by:</p><ul>
  • -</ul><h4>Radiographic features</h4><p>On CT the finding that should not be missed is that of a hyperdense basilar artery and imaging features are discussed further in the more general article on <a href="/articles/acute-basilar-artery-occlusion">acute basilar artery occlusion</a>. </p><p>Angiography (CT, MR, catheter) can be used to confirm the finding, demonstrating a filling defect. </p><h4>Differential diagnosis</h4><p>The pattern of established infarction can be mimicked by:</p><ul>
  • +</ul><h4>Radiographic features</h4><p>On CT the finding that should not be missed is that of a hyperdense basilar artery and imaging features are discussed further in the more general article on <a href="/articles/acute-basilar-artery-occlusion">acute basilar artery occlusion</a>. </p><p>Angiography (CT, MR, catheter) can be used to confirm the finding, demonstrating a filling defect. </p><h4>Differential diagnosis</h4><p>The pattern of established infarction can be mimicked by:</p><ul>
  • -<li>bilateral internal cerebral vein thrombosis (<a href="/articles/dural-venous-sinus-thrombosis">dural venous sinus thrombosis</a>)</li>
  • +<li>bilateral internal cerebral vein thrombosis (<a href="/articles/dural-venous-sinus-thrombosis">dural venous sinus thrombosis</a>)</li>

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