Typical clinical manifestations of multiple myeloma (mnemonic)
Last revised by Daniel J Bell on 21 Dec 2019
Citation, DOI, disclosures and article data
Citation:
Knipe H, Bell D, Typical clinical manifestations of multiple myeloma (mnemonic). Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-70874
Permalink:
rID:
70874
Article created:
Disclosures:
At the time the article was created Henry Knipe had no recorded disclosures.
View Henry Knipe's current disclosures
Last revised:
21 Dec 2019,
Daniel J Bell ◉
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
2 times, by
2 contributors -
see full revision history and disclosures
Systems:
Sections:
Tags:
Synonyms:
- CRAB (mnemonic)
The typical clinical manifestations of multiple myeloma can be recalled using the mnemonic:
- CRAB
Mnemonic
- C: hypercalcemia
- R: renal failure
- A: anemia
- B: bone disease
The CRAB mnemonic can help differentiate multiple myeloma from its precursor diseases - monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma 2.
References
- 1. Alípio G. Ormond Filho, Bruno C. Carneiro, Daniel Pastore, Igor P. Silva, Sâmia R. Yamashita, Flávio D. Consolo, Vânia T. M. Hungria, Alex F. Sandes, Edgar G. Rizzatti, Marcelo A. C. Nico. Whole-Body Imaging of Multiple Myeloma: Diagnostic Criteria. (2019) RadioGraphics. 39 (4): 1077-1097. doi:10.1148/rg.2019180096 - Pubmed
- 2. Nakaya A, Fujita S, Satake A, Nakanishi T, Azuma Y, Tsubokura Y, Hotta M, Yoshimura H, Ishii K, Ito T, Nomura S. Impact of CRAB Symptoms in Survival of Patients with Symptomatic Myeloma in Novel Agent Era. (2017) Hematology reports. 9 (1): 6887. doi:10.4081/hr.2017.6887 - Pubmed
Unable to process the form. Check for errors and try again.