Ulegyria refers to a shrunken and flattened cortex usually due to global hypoxic ischemic injury in term infants, centering on the deepest portion of gyri, usually in the parasagittal region. It is here that perfusion is most tenuous and, therefore, most susceptible to ischemic damage.
It is one of the leading causes of posterior cortex epilepsy 2.
A mushroom-shaped morphology of gyri is the characteristic apperance of ulegyria.
- 1. Villani F, D'Incerti L, Granata T et-al. Epileptic and imaging findings in perinatal hypoxic-ischemic encephalopathy with ulegyria. Epilepsy Res. 2003;55 (3): 235-43. Pubmed citation
- 2. Usui N, Mihara T, Baba K et-al. Posterior cortex epilepsy secondary to ulegyria: is it a surgically remediable syndrome?. Epilepsia. 2008;49 (12): 1998-2007. doi:10.1111/j.1528-1167.2008.01697.x - Pubmed citation