Wharton jelly

Changed by Bruno Di Muzio, 2 Sep 2017

Updates to Article Attributes

Body was changed:

Wharton jelly refers to the gelatinous substance within the umbilical cord.

Gross anatomy

Wharton jelly is derived from extra-embryonic mesoderm and is largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfatesulphate) while containing smaller amounts of fibroblasts and macrophages. It acts as a supportivesupport structure and protects the vessels of the umbilical cord against compression and constriction.

Related pathology

History and etymology

Named after the English physician Thomas Wharton (1614-1673) 1.

  • -<p><strong>Wharton jelly </strong>refers to the gelatinous substance within the <a href="/articles/umbilical-cord">umbilical cord</a>.</p><h4>Gross anatomy</h4><p>Wharton jelly is derived from extra-embryonic mesoderm and is largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate) while containing smaller amounts of fibroblasts and macrophages. It acts as a supportive structure and protects the vessels of the umbilical cord against compression and constriction.</p><ul></ul><h4>Related pathology</h4><ul>
  • +<p><strong>Wharton jelly </strong>refers to the gelatinous substance within the <a href="/articles/umbilical-cord">umbilical cord</a>.</p><h4>Gross anatomy</h4><p>Wharton jelly is derived from extra-embryonic mesoderm and is largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulphate) while containing smaller amounts of fibroblasts and macrophages. It acts as a support structure and protects the vessels of the umbilical cord against compression and constriction.</p><ul></ul><h4>Related pathology</h4><ul>
  • -<li>below 10<sup>th</sup> percentile of cord thickness for gestational age</li>
  • +<li>below the 10<sup>th</sup> percentile of cord thickness for gestational age</li>

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