Splenic tuberculomas with tubercular psoas abscess
Splenic calcifications usually represent sequelae of a previous acute lesions and are a nonspecific finding. The causes are numerous, including infections, such as histoplasmosis (Histoplasma capsulatum), tuberculosis, brucellosis (Brucella abortus), candidiasis, Pneumocystis jiroveci and sickle cell disease.
Single or smaller numbers of calcified lesions can also be seen following trauma and ischemia/infarction.
Calcification can also be associated with splenic hemangiomas and cysts. Rarely, splenic calcification can be associated with non-Hodgkin lymphoma of the spleen.
Thorotrast (thorium dioxide), an alpha particle emitting contrast medium used until 1960, can also cause radio-opacification of the spleen although in a more diffuse, higher intensity appearance than that seen here.1