What is schizencephaly?
Schizencephaly is a rare cortical malformation that manifests as a grey matter-lined cleft extending from the ependyma to the pia mater, it may be either open or closed type.
What defines it to be open type schizencephaly?
In open type the cleft walls are separated and filled with CSF, which differs from closed type in which the cleft walls are opposed.
Huge left cerebral hemisphere open schizencephaly with right sided polymicrogyria. Note also the absence of the septum pellucidum.