Mirizzi syndrome

Discussion:

Mirizzi syndrome is a rare complication of gallstone disease in which a gallstone becomes impacted in the cystic duct or neck of the gallbladder causing compression of the common bile duct (CBD) or common hepatic duct, resulting in proximal obstruction. The patient may present initially with colicky epigastric pain or manifest with hyperbilirubinemia (jaundice). The obstructive jaundice can be caused by direct extrinsic compression of CHD/CBD by the stone or from fibrosis of the same caused by chronic inflammation. A cholecystocholedochal fistula can occur as a further complication to this condition if left untreated.

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