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Non-seminomatous germ cell tumor (gross pathology)

Case contributed by Andrew Ryan
Diagnosis not applicable

Presentation

Testis mass. Negative serum markers

Patient Data

Age: 30 years
Gender: Male

Orchiectomy specimen

pathology

Left testis - Much of the testis is replaced a relatively circumscribed, solid to focally cystic, pale tan tumor. The lesion is macroscopically confined to the testis. There is a cuff of residual normal tan testicular parenchyma

Case Discussion

This is an example of a non-seminomatous germ cell tumor (NSGCT) and contained areas of embryonal carcinoma and immature teratoma.

In contrast to the solid, homogenous pale appearance of seminoma, mixed germ cell tumors will more often have a mixed solid and cystic appearance and areas of congestion and hemorrhage (the latter sometimes relating to areas of choriocarcinoma).

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