Skull vault epidermoid

Discussion:

A benign, slow-growing lesion of the skull due to aberrant epidermal inclusion in the calvaria. Differential diagnosis is Langerhans cell histiocytosis in a child/young adult, metastasis and plasmacytoma. Key to diagnosis is the intradiploic location with well-demarcated lysis expanding both the inner and outer tables of the skull and well defined borders. The MRI findings of marked restricted diffusion are typical of epidermoid.

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