Patient Data
Age: 95 years
Gender: Female
From the case:
Intracystic (encysted) papillary carcinoma of breast
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The ultrasound shows a 35 mm complex cyst with:
- posterior acoustic enhancement
- low-level internal echoes (intracystic debris)
- an ovoid hyperechoic nodule (10 x 5 mm) on inner wall, projecting into the cystic lumen.
Case Discussion
In the operating theater the lesion was partially aspirated (hemorrhagic fluid) to prevent an accidental rupture and then it was completely removed under local anesthesia.
Final pathological diagnosis: intracystic papillary carcinoma, with positive estrogen and progesterone receptors , negative HER-2-neu receptor and a Ki-67 index of 8%.
The intracystic (encysted) papillary carcinoma is a rare carcinoma with incidence of 0.5% to 1% of all breast cancers, usually seen in elderly women.
It is considered as an in situ or minimally invasive neoplasm.