Giant cell tumor of bone: maxilla


Moderate sized lucent lesion within the left maxilla, splaying apart the left permanent canine and first premolar with protrusion into adjacent structures (left nasal cavity, left maxillary sinus, and left hard palate). There is limited characterization of this lesion by cone beam CT, but the appearance is suggestive of a benign neoplasm (solid) or cyst: giant cell granuloma, adenomatoid odontogenic tumor, keratocystic odontogenic tumor, Langerhans cell histiocytosis, simple bone cyst, and aneurysmal bone cyst are among the differential considerations. Definitive diagnosis will require biopsy, but preoperative MRI could provide further tissue characterization if indicated.

Subsequent biopsy confirmed the lesion to be a giant cell tumor and the lesion was treated with surgical enucleation.