Retinoblastoma - advanced


Retinoblastoma is the commonest ocular malignancy in childhood, occuring chiefly in those under 4 years of age.  This is a case of a retinoblatoma with intraorbital and intracranial extension along the optic nerve and optic chiasma with a contiguous suprasellar mass and resultant hydrocephalus in keeping with stage IV disease.

Stage IV: metastatic disease

  • A: haematogeneous metastasis without CNS involvement
    • single lesion
    • multiple lesions or


  • B: CNS metastatic involvement
    1. pre-chiasmatic lesion
    2. CNS mass
    3. leptomeningeal disease