Transitional cell carcinoma of renal pelvis

Case contributed by Bruno Di Muzio
Diagnosis certain

Presentation

Hematuria.

Patient Data

Age: 85 years

In the pelvis, artefact from the left hip prosthesis obscures the urinary trigone. There is mild distension of the left renal pelvis which contains enhancing soft tissue consistent with transitional cell carcinoma. No parenchymal invasion is identified. There is minimal contrast hold up. No ureteral lesion is identified. A few tiny calculi are present within the calyces of the left. The  urinary bladder is properly distended and shows no mural thickening. Liver is normal size with no focal lesion. Spleen, pancreas, adrenal glands and right kidney are unremarkable. No retroperitoneal lymphadenopathy. Small saccular infrarenal abdominal aortic aneurysm measuring less than 3 cm in size. Extensive diverticular disease with no evidence of acute inflammation. No destructive lesion in the bones. In the lungs, there is consolidation in the right lower lobe that may be related to aspiration.

US renal tract

ultrasound

One month later, ultrasound demonstrates a moderate left hydronephrosis and irregular thickening of the renal pelvis wall consistent with tumoral involvement. 

Case Discussion

This case was confirmed to be a transitional cell carcinoma. Urine cytology: 

MACROSCOPIC DESCRIPTION: 50ml clear straw colored fluid.

MICROSCOPIC DESCRIPTION: The smears contain malignant urothelial cells, with benign transitional cells, renal tubular epithelial cells, squamous cells, necrotic cellular debris, crystal and red blood cells.

DIAGNOSIS: Urothelial cell carcinoma.

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