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The Gout (James Gillray, 1799) depicts the pain of the artist's podagra as a demon or dragon.
James Gillray (1756-1815) was a British caricaturist and printmaker famous for his distinct style of political and social satire cartoons and hence his iconic status as the father of the political cartoon.
The original image can be found at: https://commons.wikimedia.org/wiki/File:The_gout_james_gillray.jpg. (This image is free of copyright and can be used without any license requirements).