Microcephaly with a simplified gyral pattern. This imaging series demonstrates delayed but progressive cerebral development. Small head size became evident progressively on pre-natal imaging, and the head circumference <3SD postnatally confirms the diagnosis of microcephaly. 

There were no associated cerebral abnormalities in this case, however microcephaly may be associated with cortical malformations, dysgenesis of corpus callosum and dysplasia or hypoplasia of the brainstem and cerebellum.

Interestingly, the associated bilateral persistent hyperplastic primary vitreous was only evident on the post-natal MRI.