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Acromegaly

Case contributed by Paresh K Desai
Diagnosis almost certain
x-ray

AP radiograph of the hand shows ungal tufting, widening of the bases of distal phalanges, metacarpal osteophytes on radial aspect (metacarpal hooks) and soft tissue hypertrophy.

x-ray

Lateral radiograph of skull reveals enlarged sella with double flooring, thickened skull vault, pneumosinus dilatans and prognathism.

Case Discussion

Acromegaly is the result of excessive growth hormone (GH) production in skeletally mature patients, most commonly from an adenoma of the pituitary.

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