Mediastinal metastases - clear cell RCC


This case shows well-defined hypervascular anterior mediastinum masses in an adult patient with a previous medical history of left nephrectomy 5 years ago. The imaging features are not those of lymphoma, a thymic carcinoma would be unlikely to present as multiple hypervascular lesions such as these. The appearances are highly concerning for hypervascular metastases, likely from a renal cell carcinoma in this scenario. 

FNA was performed and confirmed metastases from clear cell renal cell carcinoma, which was further confirmed to be the primary tumor that led to a left nephrectomy.