Pseudocirrhosis most often is used to describe the morphologic changes of cirrhosis developing in patients with metastatic breast cancer after chemotherapy. 

The pathophysiology of pseudocirrhosis can be due to scarring/capsular retraction following chemotherapy, desmoplastic reaction due to infiltrative metastases, and nodular regenerative hyperplasia ¹.

Thus, pseudocirrhosis can represent treatment response or active metastases in the liver. 

In this case, the enlargement of the liver supports the pathologic diagnosis of active, infiltrative tumor throughout the liver. Notice how much the right kidney is inferiorly displaced on the follow-up exam due to hepatic enlargement.

The areas of reticular/branching fibrosis are likely related to a combination of fibrosis/desmoplastic reaction from the infiltrative tumor and liver injury from cholestasis and venous congestion. 

See more cases: Pseudocirrhosis playlist