Presentation
History of colorectal carcinoma. Follow-up from PET avid lumbar spine lesion.
Patient Data
T1 hypointense / T2 hyperintense lesion centered on the L3 inferior endplate involving both intervertebral disc and vertebral body. The inferior endplate cortex appears to be superiorly displaced by the lesion (best seen on the sagittal T2FS sequence) with surrounding post-contrast enhancement. No other bone lesion.
The patient was referred for a CT guided bone biopsy.
Large lucent lesion centered on the inferior portion of the L3 vertebral body with an apparent loss of the inferior endplate. Mild surrounding bony sclerosis.
A transpedicular bone biopsy was performed.
Histopathology report
MICROSCOPIC DESCRIPTION: The sections show multiple fragments of bone and crushed marrow content. No evidence of malignancy is seen. No active inflammation is present.
DIAGNOSIS: L3 vertebral body lesion Bx: Unremarkable bone and crushed marrow content. No evidence of malignancy seen. Immunohistochemistry will be performed to help exclude a subtle metastatic carcinoma and an addendum report will follow.
SUPPLEMENTARY REPORT Immunohistochemistry is negative with AE1/AE3 and CAM5.2. No evidence of carcinoma is seen.
Case Discussion
The findings on the MRI are suggestive of an acute Schmorl node with a T2 hyperintense lesion involving the disc. Surrounding edema and post-contrast enhancement, as seen in this case, can be seen in acute herniations but given the history, there was a concern for metastatic disease which precipitated the Schmorl node formation, thus the reason for bone biopsy.