Brainstem ganglioglioma

Case contributed by Dr Hani Salam


Dizziness, vertigo, and nystagmus

Patient Data

Age: 6 years
Gender: Male

Ganglioglioma centered on the left middle cerebellar peduncle.

Case Discussion

Pathologically-proven ganglioglioma

Pathology report:


  • GFAP+, Ki-67 very focally increased, NEU-N-, NFP, P53+, SYNAPT+


brainstem tumor:
cerebellar tissue, no neoplasm seen

Although most gangliogliomas are of WHO grade I, with no definitive established criteria for grade II ganglioglioma, this tumor shows a diffuse pattern, as demonstrated on NFP immunostain and very focal increase in Ki-67 proliferation index. The overall features probably favor more grade II ganglioglioma.

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Case information

rID: 10763
Published: 18th Sep 2010
Last edited: 17th Oct 2019
Inclusion in quiz mode: Included

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