Centrilobular emphysema - severe

Case contributed by Dr Bruno Di Muzio


Shortness of breath developing during exertion. She is a heavy smoker. FEV1/FVC < 70%.

Patient Data

Age: 70 years
Gender: Female

CT Chest

Lucent regions with imperceptible walls involving the upper lobes, and superior segments of the lower lobes bilaterally. Is clear the presence of centrilobular emphysema in the upper zones of the lungs. Also noted small bubbles of paraseptal emphysema.  

Case Discussion

This patient is a Stage II: moderate COPD. The diagnosis of COPD is through spirometry. 

Pulmonary emphysema is defined as the "abnormal permanent enlargement of the airspaces distal to the terminal bronchioles accompanied by destruction of the alveolar wall and without obvious fibrosis".

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Case information

rID: 21122
Published: 5th Jan 2013
Last edited: 16th Jul 2018
System: Chest
Inclusion in quiz mode: Excluded

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