Cerebral toxoplasmosis

Case contributed by Juan José Gómez Muga
Diagnosis almost certain

Presentation

Dizziness.

Patient Data

Age: 40 years
Gender: Male
ct

Incomplete ring enhancing lesion with vasogenic edema and mild mass effect in the left parietal lobe.

Hypodense lesions in the right basal ganglia and right cerebellar hemisphere.

Cortical calcification in the right poscentral gyrus.

mri

Multiple T2/FLAIR-hyperintense, contrast-enhancing lesions in the left parietal lobe, left occipital lobe, left hippocampus, right caudate, and both cerebellar hemispheres.

"Eccentric target sign" in left hippocampus and cerebellar lesions.

No restriction on DWI/ADC. Low rCBV values. High lipid peak and reduced Cho, Cr and NAA on MRS. Findings are suggestive of non-pyogenic brain abscesses or metastatic disease.

Eccentric target sign is suggestive of toxoplasmosis.

Case Discussion

Serology:

  • HIV + 
  • Toxoplasma IgG +

CD4 < 100.

Anti-toxoplasma therapy was initiated with the resolution of the findings.​

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.