Presentation
Epilepsy.
Patient Data
Age: 30 years
Gender: Female
From the case:
Closed-lip schizencephaly with a focal cortical dysplasia
{"current_user":null,"step_through_annotations":true,"access":{"can_edit":false,"can_download":true,"can_toggle_annotations":true,"can_feature":false,"can_examine_pipeline_reports":false,"can_pin":false},"extraPropsURL":"/studies/94255/annotated_viewer_json?lang=us"}
The MRI sequences demonstrate:
- an abnormal grey matter extending from the left frontal cortex to the body of the lateral ventricle with a slight indentation of the ventricular wall, in keeping with a closed-lip schizencrphsly with polymicrogyria
- there is an adjacent cortical thickening extending from the cortex to the ventricle of low signal on T1, high signal on T2/FLAIR, and DWI. The mean ADC value at the lesion was 1.019 × 10−3 mm2/s higher than that measured at the contralateral normal region (0.742 × 10−3 mm2/s) with blurring of the grey/white matter junction and abnormal adjacent gyri and sulci, indicating most likely an associated focal cortical dysplasia
- absent septum pellucidum with small optic chiasma which may represent an associated septo-optic dysplasia.
Case Discussion
The MRI features are most consistent with left closed-lip schizencephaly with associated septo-optic dysplasia and focal cortical dysplasia.
Additional contributors: R. Bouguelaa, MD, Z.E Boudiaf, MD
Unable to process the form. Check for errors and try again.