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Right upper quadrant pain for one week. Intermittent fever. Vomiting, multiple episodes
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There is a large, well-defined hypodense lesion with septations and cluster sign involving the segments VI and VII in the right lobe of the liver. It measures approximately 9.6 cm x 10 cm x 11 cm. These lesions show peripheral enhancement on the arterial phase that persist in the portal and delayed phase with non-enhancing central areas of diminished attenuation on post-contrast studies. A few enhancing septa are also present in the lesion.
The cluster sign is a finding associated with pyogenic liver abscesses. It is better appreciated on contrast-enhanced CT and MRI images. The sign describes the coalescence of multiple tiny abscesses into a single larger abscess cavity with peripheral rim enhancement on post-contrast studies, giving a clustered appearance.
- Jeffrey R, Tolentino C, Chang F, Federle M. CT of Small Pyogenic Hepatic Abscesses: The Cluster Sign. AJR Am J Roentgenol. 1988;151(3):487-489. doi:10.2214/ajr.151.3.487