Craniopharyngioma - papillary

Case contributed by A.Prof Frank Gaillard


Visual disturbance.

Patient Data

Age: 40 years
Gender: Male

MRI brain

MRI of the brain demonstrates a mass in the suprasellar region which is variegated in both T1 and T2 signal, with regions of intrinsic high T1 signal, cystic areas and solid enhancing areas. 

This patient went on to have resection of the mass. 


The tumour  comprises  solid  islands,  some with  a fragmented  and  papillary outline, of well-differentiated  squamous epithelium  embedded in a densely collagenous   and   vascularised   stroma,   which  shows  patchy   chronic inflammation. The tumour does not show  a well-developed picket fence basal epithelial layer, and stellate reticulum-like areas and wet keratin are not identified. Focally,  the tumour shows  areas of haemorrhage,  and there is one fragment showing haemorrhagic infarction. There is patchy infiltration by neutrophils.  

 DIAGNOSIS: Papillary craniopharyngioma, WHO grade 1.

Case Discussion

This case demonstrates a common appearance of papillary craniopharyngioma. 

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Case information

rID: 16812
Published: 22nd Feb 2012
Last edited: 13th Aug 2019
Inclusion in quiz mode: Included

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