Dysembryoplastic neuroepithelial tumor

Case contributed by Abdalla Al-Khashmani
Diagnosis probable

Presentation

Seizures.

Patient Data

Age: 19 years
Gender: Male

There is an intra-axial T1W hypointense subcortical lesion in the left temporo-parietal region. The T2W and FLAIR sequences show a well defined, triangular shaped, 3.5 x 3.8 x 2.6 cm hyperintense lesion with typical central bubbly appearance due to small and multiple cystic lesions divided by thin septa. There is no mass effect, edema or calcification. Adjacent skull bone does not show any change. There is no contrast enhancement as well.

Case Discussion

Imaging findings are characteristic of dysembryoplastic neuroepithelial tumor (DNET). However, oligodendroglioma, ganglioglioma, and pleomorphic xanthoastrocytoma are among the differential diagnosis, but less likely.

This teenage patient presented with seizures to a neurologist who requested an MRI. The findings are typical of DNET. They are slow growing tumors arising from either cortical or deep grey matter. They characteristically cause intractable partial seizures.

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