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Gamna-Gandy bodies (nodules)

Case contributed by Emina Talakic
Diagnosis certain

Presentation

History of portal vein thrombosis with portal congestion,. Recurrent gastrointestinal bleeding related to portal hypertensive enteropathy.

Patient Data

Age: 55 years
Gender: Male
mri

A male patient with portal vein thrombosis (with cavernous transformation) and portal hypertensive enteropathy. MR Imaging revealed splenomegaly with multiple small siderotic nodules called Gamna-Gandy bodies (nodules).

Case Discussion

Gamna-Gandy bodies are small multiple siderotic lesions in the spleen parenchyma. They contain hemosiderin, calcium, and fibrous tissue. These siderotic nodules are related to portal vein or splenic vein thrombosis, acquired hemochromatosis, hemolytic anemia, leukemia or lymphoma and they represent organized foci of hemorrhage.

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