Gastrointestinal stromal tumor of the stomach

Case contributed by Dr Achoki Daniel


Presented with dizziness. On further laboratory work-up was found to have iron deficiency anemia.

Patient Data

Age: 70 years
Gender: Male

Axial non'contrast images show a well demarcated rounded fungating soft tissue mass arising from the wall of the gastric fundus. It measures 5.14 x 5.16 x 6.52 cm (anteroposterior x mediolateral x craniocaudal).

The lesion has a deep crescent shaped ulceration.

It shows subtle heterogeneous enhancement on post-IV contrast administration.

No evidence of metastases seen.

Esophagogastroduodenoscopy showed a large ulcerated sessile mass in the fundus and cardia. No active bleeding at the time. The rest of the stomach was normal. Biopsy was done.

Gastric biopsy showed a submucosal benign mesodermal tumor consisting of haphazardly interlacing spindle cells in a hyalinized stroma. The spindle cells showed no atypia or mitotic activity. CD117/CD34IHC stained positive. The final diagnosis was Gastrointestinal Stromal Tumor (Benign)

Case Discussion

Histologically confirmed GIST projecting into the lumen of the stomach. GISTs are usually found in the stomach or small intestine. Our patient presented with symptoms of upper GI bleeding. He was 70 years old, consistent with the fact that GISTs usually occur after the age of 40 with most seen in older patients.

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Case information

rID: 54398
Published: 2nd Oct 2017
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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